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Strategies for Engineered Negligible Senescence | Wikipedia audio article

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This is an audio version of the Wikipedia Article: https://en.wikipedia.org/wiki/Strategies_for_Engineered_Negligible_Senescence 00:01:40 1 Framework 00:04:34 2 Types of aging damage and treatment schemes 00:04:45 2.1 Nuclear mutations/epimutations—OncoSENS 00:05:23 2.2 Mitochondrial mutations—MitoSENS 00:06:17 2.3 Intracellular junk—LysoSENS 00:07:10 2.4 Extracellular junk—AmyloSENS 00:07:53 2.5 Cell loss and atrophy—RepleniSENS 00:08:46 2.6 Cell senescence—ApoptoSENS 00:09:38 2.7 Extracellular crosslinks—GlycoSENS 00:10:26 3 Scientific controversy 00:13:02 3.1 iTechnology Review/i controversy 00:16:02 4 Social and economic implications 00:17:54 5 SENS meetings 00:19:55 6 SENS Research Foundation Listening is a more natural way of learning, when compared to reading. Written language only began at around 3200 BC, but spoken language has existed long ago. Learning by listening is a great way to: - increases imagination and understanding - improves your listening skills - improves your own spoken accent - learn while on the move - reduce eye strain Now learn the vast amount of general knowledge available on Wikipedia through audio (audio article). You could even learn subconsciously by playing the audio while you are sleeping! If you are planning to listen a lot, you could try using a bone conduction headphone, or a standard speaker instead of an earphone. Listen on Google Assistant through Extra Audio: https://assistant.google.com/services/invoke/uid/0000001a130b3f91 Other Wikipedia audio articles at: https://www.youtube.com/results?search_query=wikipedia+tts Upload your own Wikipedia articles through: https://github.com/nodef/wikipedia-tts Speaking Rate: 0.8684926341193994 Voice name: en-AU-Wavenet-C "I cannot teach anybody anything, I can only make them think." - Socrates SUMMARY ======= Strategies for Engineered Negligible Senescence (SENS) is the term coined by British biogerontologist Aubrey de Grey for the diverse range of regenerative medical therapies, either planned or currently in development, for the periodical repair of all age-related damage to human tissue with the ultimate purpose of maintaining a state of negligible senescence in the patient, thereby postponing age-associated disease for as long as the therapies are reapplied.The term "negligible senescence" was first used in the early 1990s by professor Caleb Finch to describe organisms such as lobsters and hydras, which do not show symptoms of aging. The term "engineered negligible senescence" first appeared in print in Aubrey de Grey's 1999 book The Mitochondrial Free Radical Theory of Aging, and was later prefaced with the term "strategies" in the article Time to Talk SENS: Critiquing the Immutability of Human Aging De Grey called SENS a "goal-directed rather than curiosity-driven" approach to the science of aging, and "an effort to expand regenerative medicine into the territory of aging". To this end, SENS identifies seven categories of aging "damage" and a specific regenerative medical proposal for treating each. While many biogerontologists find it "worthy of discussion" and SENS conferences feature important research in the field, some contend that the ultimate goals of de Grey's programme are too speculative given the current state of technology, referring to it as "fantasy rather than science".
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